Sodium Hydroxide → HCID 23445637, compound

Participants

Reaction Steps

The tide compound was prepared according to the procedure in Example 6, step 3 using 6-methoxy-5-methyl-biphenyl-3-carbaldehyde (1.53 g, 6.77 mmol), silver (I) oxide (1.56 g, 6.77 mmol) and NaOH (2.71 g, 67.7 mmol) to give 1.46 g (89%) of the title compound as a white solid, mp 165-168° C. 1H NMR (DMSO-d6) δ2.34 (s, 3 H), 3.36 (s, 3 H), 7.38-7.55 (m, 5 H), 7.71 (d, 1 H), 7.81 (dd, 1 H). IR (KBr) 3400, 2950, 1700, 1600 and 1410 cm−1. mass spectrum (EI), m/z 242 (M+). Anal. Calcd. for C15H14O30.2 H2O: C, 73.27; H, 5.91; N, 0.00. Found: C, 73.21; H, 5.93; N, 0.17.

Provenance & Evidence