HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-p-anisaldehyde → (e)-3-(3-Fluoro-4-methoxyphenyl)-1-(2-hydroxy-5-methyl-3-nitrophenyl)-2-propen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-p-anisaldehyde | HCID 67696 | — |
| Reactant | 2'-Hydroxy-5'-methyl-3'-nitroacetophenone | HCID 736162 | — |
| Product | (e)-3-(3-Fluoro-4-methoxyphenyl)-1-(2-hydroxy-5-methyl-3-nitrophenyl)-2-propen-1-one | HCID 23444787 | 75.2% |
Reaction Steps
2-Hydroxy-5-methyl-3-nitroacetophenone (100 mg, 0.51 mmol) and 4-methoxy-3-fluorobenzaldehyde (95 mg, 0.61 mmol) were reacted according to the same procedure as Preparation 22 to give 127 mg (Yield 74%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683095B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-b2048dc5aea94f9ca93f64b5496b78ba |
| Source note | uspto-grants-2004_01 |