HuagongsheHuagongshe Chemistry Print Report · For research reference only
2'-Hydroxy-5'-methyl-3'-nitroacetophenone → (e)-3-[4-(Benzyloxy)-3-chlorophenyl]-1-(2-hydroxy-5-methyl-3-nitrophenyl)-2-propen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2'-Hydroxy-5'-methyl-3'-nitroacetophenone | HCID 736162 | — |
| Reactant | 4-(Benzyloxy)-3-chlorobenzaldehyde | HCID 2735495 | — |
| Product | (e)-3-[4-(Benzyloxy)-3-chlorophenyl]-1-(2-hydroxy-5-methyl-3-nitrophenyl)-2-propen-1-one | HCID 23444715 | 59.6% |
Reaction Steps
2-Hydroxy-5-methyl-3-nitroacetophenone (750 mg, 3.84 mmol) and 4-benzyloxy-3-chlorobenzaldehyde (1 g, 3.84 mmol) were reacted according to the same procedure as Preparation 15 to give 970 mg (Yield 59%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683095B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-7c6b49b82c234c259ae9ece2bbfc5bc9 |
| Source note | uspto-grants-2004_01 |