2'-Hydroxy-5'-methyl-3'-nitroacetophenone → HCID 23444756, compound

HRID 1841366Notes

Reaction equation

HRID 1841366 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]([CH3:10])=[O:9])[C:5]([OH:11])=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1.[CH2:15]([O:22][C:23]1[CH:30]=[C:29]([O:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:28]=[CH:27][C:24]=1[CH:25]=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([O:22][C:23]1[CH:30]=[C:29]([O:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:28]=[CH:27][C:24]=1/[CH:25]=[CH:10]/[C:8]([C:6]1[CH:7]=[C:2]([CH3:1])[CH:3]=[C:4]([N+:12]([O-:14])=[O:13])[C:5]=1[OH:11])=[O:9])[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 7361622'-Hydroxy-5'-methyl-3'-nitroacetophenoneHCID 18090802,4-Bis(benzyloxy)benzaldehyde

Product 1

HCID 23444756HCID 23444756, compoundYield 43%

Procedure

2-Hydroxy-5-methyl-3-nitroacetophenone (500 mg, 2.56 mmol) and 2,4-dibenzyloxybenzaldehyde (900 mg, 2.83 mmol) were reacted according to the same procedure as Preparation 22 to give 540 mg (Yield 43%) of the title compound.

Workup

  1. customaccording to the same procedure as Preparation 22

Sources & evidence

ORD record
ord-7ba927a7692a4fb6a316db4efb490eaa
Source dataset
uspto-grants-2004_01
Patent number
US06683095B2

Reaction notes

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