2'-Hydroxy-5'-methyl-3'-nitroacetophenone → HCID 23444783, compound

HRID 1841369Notes

Reaction equation

HRID 1841369 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]([CH3:10])=[O:9])[C:5]([OH:11])=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1.[CH2:15]([O:18][C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][C:20]=1[CH2:27][O:28][CH2:29][CH:30]=[CH2:31])[CH:16]=[CH2:17]>>[CH2:15]([O:18][C:19]1[CH:26]=[CH:25][C:22](/[CH:23]=[CH:10]/[C:8]([C:6]2[CH:7]=[C:2]([CH3:1])[CH:3]=[C:4]([N+:12]([O-:14])=[O:13])[C:5]=2[OH:11])=[O:9])=[CH:21][C:20]=1[CH2:27][O:28][CH2:29][CH:30]=[CH2:31])[CH:16]=[CH2:17]

Participants

3

Reactant 2

HCID 7361622'-Hydroxy-5'-methyl-3'-nitroacetophenoneHCID 10704725HCID 10704725, compound

Product 1

HCID 23444783HCID 23444783, compoundYield 45%

Procedure

2-Hydroxy-5-methyl-3-nitroacetophenone (500 mg, 2.56 mmol) and 4-(allyloxy)-3-[(allyloxy)methyl]benzaldehyde (760 mg, 3.27 mmol) were reacted according to the same procedure as Preparation 22 to give 470 mg (Yield 45%) of the title compound.

Workup

  1. customaccording to the same procedure as Preparation 22

Sources & evidence

ORD record
ord-d5009ac3c74e40bbbac0077eb6d06732
Source dataset
uspto-grants-2004_01
Patent number
US06683095B2

Reaction notes

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