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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841381Generated: November 4, 2026

Boronic acid, (4-ethylphenyl)- → N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole

https://huagongshe.com/reaction/1841381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic acid, (4-ethylphenyl)-HCID 2734352—
ReactantN-(5-bromothiophenesulfonyl)pyrroleHCID 23445587—
ProductN-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrroleHCID 2344538281%

Reaction Steps

N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole was prepared, in the same manner as described in Example 13C, from 4-ethylphenylboronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as a tan solid in 81% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683103B2
Source datasetuspto-grants-2004_01
ORD IDord-7662d12955d04eef901e24875ffe4228
Source noteuspto-grants-2004_01