HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 11175237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate | HCID 11173351 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 11175237 | HCID 11175237 | 78.5% |
Reaction Steps
Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate (350 mg, 1.28 mmol) and 1-phenylpiperazine (208 mg, 1.28 mmol) were dissolved in anhydrous tetrahydrofuran and thereto DBU (195 mg, 1.28 mmol) was added. The resulting mixture was stirred at room temperature for 2 hours and concentrated under the reduced pressure to remove the solvent, and purified by column chromatography to obtain the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683184B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-0e07e65271554ceab893f5478e09335a |
| Source note | uspto-grants-2004_01 |