1-(2-Fluorophenyl)piperazine → HCID 23446176, compound

HRID 1841454Notes

Reaction equation

HRID 1841454 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12](=[O:20])OC2C=CC=CC=2)[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8].[F:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[N:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[CH3:1][C:2]1[N:3]=[C:4]([NH:11][C:12]([N:31]2[CH2:30][CH2:29][N:28]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=3[F:21])[CH2:33][CH2:32]2)=[O:20])[C:5]([O:9][CH3:10])=[N:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 11173351Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate

Product 1

HCID 23446176HCID 23446176, compoundYield 74.5%

Procedure

Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate and 1-(2-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-9662c9908d4047fcbb08e756e5044630
Source dataset
uspto-grants-2004_01
Patent number
US06683184B2

Reaction notes

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