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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841457Generated: November 4, 2026

1-(3,5-Difluorophenyl)piperazine → 1-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminocarbonyl]-4-(3,5-difluorophenyl)piperazine

https://huagongshe.com/reaction/1841457

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Difluorophenyl)piperazineHCID 10987219—
ReactantPhenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamateHCID 11173351—
Product1-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminocarbonyl]-4-(3,5-difluorophenyl)piperazineHCID 2344636378%

Reaction Steps

Phenyl N-(5,6-dimethyl-2-methoxypyrazin-3-yl)carbamate and 1-(3,5-difluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683184B2
Source datasetuspto-grants-2004_01
ORD IDord-d24c4eed404742e8ad80fd207983a0d4
Source noteuspto-grants-2004_01