1-(2,3,5,6-Tetramethylphenyl)piperazine → 1-[(2-Methoxyquinoxalin-3-yl)aminocarbonyl]-4-(2,3,5,6-tetramethylphenyl)piperazine

HRID 1841476Notes

Reaction equation

HRID 1841476 reaction equation
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[O:22])OC2C=CC=CC=2)=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[CH3:23][C:24]1[C:29]([CH3:30])=[CH:28][C:27]([CH3:31])=[C:26]([CH3:32])[C:25]=1[N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:36]2[CH2:37][CH2:38][N:33]([C:25]3[C:26]([CH3:32])=[C:27]([CH3:31])[CH:28]=[C:29]([CH3:30])[C:24]=3[CH3:23])[CH2:34][CH2:35]2)=[O:22])=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

Participants

3

Reactant 2

HCID 234461571-(2,3,5,6-Tetramethylphenyl)piperazineHCID 23446261Phenyl N-(2-methoxyquinoxalin-3-yl)carbamate

Product 1

HCID 234463511-[(2-Methoxyquinoxalin-3-yl)aminocarbonyl]-4-(2,3,5,6-tetramethylphenyl)piperazineYield 64%

Procedure

Phenyl N-(2-methoxyquinoxalin-3-yl)carbamate and 1-(2,3,5,6-tetramethylphenyl)piperazine were reacted by the same way with the example 36 to obtain the titled compound.

Sources & evidence

ORD record
ord-7926f37cc4e4408d87bcadef3d3ad96f
Source dataset
uspto-grants-2004_01
Patent number
US06683184B2

Reaction notes

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