1-(2-Methoxyphenyl)piperazine → 1-[(2-Methoxyquinoxalin-3-yl)aminothiocarbonyl]-4-(2-met-hoxyphenyl)piperazine

Beteiligte Stoffe

Reaktionsschritte

Phenyl N-(2-methoxyquinoxalin-3-yl)thiocarbamate (215 mg, 0.69 mmol) and 1-(2-methoxyphenyl)piperazine (154 mg, 0.69 mmol) were dissolved in anhydrous tetrahydrofuran (25 ml) and thereto DBU (105 mg, 0.69 mmol) was added. The mixture was stirred at room temperature for 2 hours, concentrated under the reduced pressure to remove the solvent and purified by column chromatography to obtain the titled compound.

Herkunft & Nachweise