1-(3,5-Dimethylphenyl)piperazine → 1-[(2-Methoxyquinoxalin-3-yl)aminothiocarbonyl]-4-(3,5-di-methylphenyl)piperazine

HRID 1841489Notes

Reaction equation

HRID 1841489 reaction equation
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[S:22])OC2C=CC=CC=2)=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[CH3:23][C:24]1[CH:25]=[C:26]([N:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)[CH:27]=[C:28]([CH3:30])[CH:29]=1>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:34]2[CH2:35][CH2:36][N:31]([C:26]3[CH:27]=[C:28]([CH3:30])[CH:29]=[C:24]([CH3:23])[CH:25]=3)[CH2:32][CH2:33]2)=[S:22])=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

Participants

3

Reactant 2

HCID 27586261-(3,5-Dimethylphenyl)piperazineHCID 53676590Phenyl N-(2-methoxyquinoxalin-3-yl)thiocarbamate

Product 1

HCID 179225931-[(2-Methoxyquinoxalin-3-yl)aminothiocarbonyl]-4-(3,5-di-methylphenyl)piperazineYield 65%

Procedure

Phenyl N-(2-methoxyquinoxalin-3-yl)thiocarbamate and 1-(3,5-dimethylphenyl)piperazine were reacted by the same way with the example 63 to obtain the titled compound.

Sources & evidence

ORD record
ord-f1c94a1a6de74179bb67beaeee1f2b71
Source dataset
uspto-grants-2004_01
Patent number
US06683184B2

Reaction notes

Loading…