Piperazin-4-ylacetophenone → 1-[(2-Methoxyquinoxalin-3-yl)aminothiocarbonyl]-4-(4-acetylphenyl)piperazine

HRID 1841493Notes

Reaction equation

HRID 1841493 reaction equation
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[S:22])OC2C=CC=CC=2)=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[C:23]([C:26]1[CH:31]=[CH:30][C:29]([N:32]2[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]2)=[CH:28][CH:27]=1)(=[O:25])[CH3:24]>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:35]2[CH2:34][CH2:33][N:32]([C:29]3[CH:28]=[CH:27][C:26]([C:23](=[O:25])[CH3:24])=[CH:31][CH:30]=3)[CH2:37][CH2:36]2)=[S:22])=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

Participants

3

Reactant 2

HCID 97269Piperazin-4-ylacetophenoneHCID 53676590Phenyl N-(2-methoxyquinoxalin-3-yl)thiocarbamate

Product 1

HCID 536422441-[(2-Methoxyquinoxalin-3-yl)aminothiocarbonyl]-4-(4-acetylphenyl)piperazineYield 56.9%

Procedure

Phenyl N-(2-methoxyquinoxalin-3-yl)thiocarbamate and 1-(4-acetylphenyl)piperazine were reacted by the same way with the example 63 to obtain the titled compound.

Sources & evidence

ORD record
ord-14afbe02698f4f5e85edf9baf77398a6
Source dataset
uspto-grants-2004_01
Patent number
US06683184B2

Reaction notes

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