1-(2-Ethoxyphenyl)piperazine → 1-[(2-Ethoxyquinoxalin-3-yl)aminocarbonyl]-4-(2-ethoxyphenyl)piperazine

HRID 1841496Notes

Reaction equation

HRID 1841496 reaction equation
[CH2:1]([O:3][C:4]1[C:13]([NH:14][C:15](=[O:23])OC2C=CC=CC=2)=[N:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=1)[CH3:2].[CH2:24]([O:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)[CH3:25]>>[CH2:1]([O:3][C:4]1[C:13]([NH:14][C:15]([N:36]2[CH2:35][CH2:34][N:33]([C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=3[O:26][CH2:24][CH3:25])[CH2:38][CH2:37]2)=[O:23])=[N:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=1)[CH3:2]

Participants

3

Reactant 2

HCID 833571-(2-Ethoxyphenyl)piperazineHCID 23446273Phenyl N-(2-ethoxyquinoxalin-3-yl)carbamate

Product 1

HCID 234462531-[(2-Ethoxyquinoxalin-3-yl)aminocarbonyl]-4-(2-ethoxyphenyl)piperazineYield 76.5%

Procedure

Phenyl N-(2-ethoxyquinoxalin-3-yl)carbamate and 1-(2-ethoxyphenyl)-piperazine were reacted by the same way with the example 36 to obtain the titled compound.

Sources & evidence

ORD record
ord-82a9a2abf8d743bba3ccaca8dc61b84e
Source dataset
uspto-grants-2004_01
Patent number
US06683184B2

Reaction notes

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