HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [4-(4-Dimethylamino-butoxy)-phenyl]-carbamic acid tert-butyl ester hydrobromid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | [4-(4-Bromo-butoxy)-phenyl]-carbamic acid tert-butyl ester | HCID 68615222 | — |
| Product | [4-(4-Dimethylamino-butoxy)-phenyl]-carbamic acid tert-butyl ester hydrobromid | HCID 131724326 | — |
Reaction Steps
In analogy to example 1.8, reaction of [4-(4-Bromo-butoxy)-phenyl]-carbamic acid tert-butyl ester with 10 eq dimethylamine (33% in ethanol, 5.6 M) yielded (without extraction with aqueous saturated NaHCO3 solution) [4-(4-Dimethylamino-butoxy)-phenyl]-carbamic acid tert-butyl ester hydrobromid (1:1), MS: 309 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683201B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-e5045b08aad64d2bac85defc04370e5a |
| Source note | uspto-grants-2004_01 |