4-Chlorophenyl chloroformate → (4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester

HRID 1841596Notes

Reaction equation

HRID 1841596 reaction equation
S([O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][CH3:13])=[CH:8][CH:7]=1)(O)(=O)=O.[CH:14]1[C:19]([O:20][C:21](Cl)=[O:22])=[CH:18][CH:17]=[C:16]([Cl:24])[CH:15]=1>>[Cl:24][C:16]1[CH:17]=[CH:18][C:19]([O:20][C:21](=[O:22])[N:12]([C:9]2[CH:10]=[CH:11][C:6]([OH:5])=[CH:7][CH:8]=2)[CH3:13])=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 1390594-Chlorophenyl chloroformateHCID 10198132p-(N-methylamino)phenol sulfate

Product 1

HCID 68614626(4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester

Procedure

In analogy to example 15.1, reaction of 4-methylaminophenol hemisulfate with 4-chlorophenylchloroformate yielded (4-Hydroxy-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester, mp: 143-145° C., dec.; MS: 278 (MH+, 1Cl).

Sources & evidence

ORD record
ord-db1c3b80328e40de971e58b82c93fac1
Source dataset
uspto-grants-2004_01
Patent number
US06683201B2

Reaction notes

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