2-(Ethylamino)ethanol → HCID 10202342, compound

HRID 1841600Notes

Reaction equation

HRID 1841600 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:24])[N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22]Br)=[CH:14][CH:13]=2)[CH3:11])=[CH:4][CH:3]=1.[CH2:25]([NH:27][CH2:28][CH2:29][OH:30])[CH3:26]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:24])[N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][N:27]([CH2:25][CH3:26])[CH2:28][CH2:29][OH:30])=[CH:14][CH:13]=2)[CH3:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 80722-(Ethylamino)ethanolHCID 68615035HCID 68615035, compound

Product 1

HCID 10202342HCID 10202342, compound

Procedure

In analogy to example 17.1, reaction of [4-(4-Bromo-butoxy)-phenyl]-methyl-carbamic acid 4-chloro-phenyl ester with 2-ethylaminoethanol yielded (4-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-butoxy}-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester, MS: 421 (MH+).

Sources & evidence

ORD record
ord-a1695f7696dd4bc1bbd15b70981999d7
Source dataset
uspto-grants-2004_01
Patent number
US06683201B2

Reaction notes

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