Dimethylamine → HCID 86584775, compound

HRID 1841601Notes

Reaction equation

HRID 1841601 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:24])[N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22]Br)=[CH:14][CH:13]=2)[CH3:11])=[CH:4][CH:3]=1.[CH3:25][NH:26][CH3:27]>>[CH:9]([OH:24])=[O:8].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:24])[N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][N:26]([CH3:27])[CH3:25])=[CH:14][CH:13]=2)[CH3:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 68615035HCID 68615035, compound

Product 1

HCID 86584775HCID 86584775, compound

Procedure

In analogy to example 17.1, reaction of [4-(4-Bromo-butoxy)-phenyl]-methyl-carbamic acid 4-chloro-phenyl ester with 10 eq dimethylamine (33% in ethanol, 5.6 M) yielded [4-(4-Dimethylamino-butoxy)-phenyl]-methyl-carbamic acid 4-chloro-phenyl ester; compound with formic acid, MS: 377 (MH+).

Sources & evidence

ORD record
ord-7bee95063ef74effb25b8c4d16789881
Source dataset
uspto-grants-2004_01
Patent number
US06683201B2

Reaction notes

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