HCID 15542160, compound → HCID 15542161, compound

Participants

Reaction Steps

To a solution of 1-[(1S)-1-benzyl-2-(benzyloxy)ethyl]-3-[2-(dimethylamino)ethyl]-3-phenethyl urea (Compound 2-1, 414 mg) in ethanol (4.5 ml), there was added 20% palladium hydroxide-on-carbon (100 mg) in the nitrogen gas atmosphere. This mixture was stirred for 3 days in the hydrogen gas atmosphere. The palladium-on-carbon was removed by the filtration through celite and the resulting filtrate was concentrated under reduced pressure to thus give the title compound (Compound 3-1, 299 mg).

Provenance & Evidence