HCID 23446817, compound → HCID 23446811, compound

Participants

Reaction Steps

N-Benzoyloxy-2-(4-chloro-phenyl)-N-[2-(3-methoxy-4-prop-2-ynyloxy-phenyl)-ethyl]-acetamide (0.3 g, 0.6 mmol) is dissolved in 2 ml 10% NH4OH/MeOH and stirred at room temperature overnight. The solvent is removed under vacuum and the crude product is purified by flash chromatography (ethyl acetate:hexane, 1:2) to yield 2-(4-chloro-phenyl)-N-hydroxy-N-[2-(3-methoxy-4-prop-2-ynyloxy-phenyl)-ethyl]-acetamide as a solid.

Provenance & Evidence