HCID 86158515, compound → HCID 19372161, compound

HRID 1841873Notes

Reaction equation

HRID 1841873 reaction equation
[CH3:1][O:2][C:3](=[O:22])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]=[N+]=[N-]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:22])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][NH2:19]

Participants

4

Reactant 1

HCID 86158515HCID 86158515, compound

Product 1

HCID 19372161HCID 19372161, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

16-azidohexadecanoic acid methyl ester is catalytically hydrogenated with palladium/activated charcoal in methanol at 3 bar for three hours to give the corresponding amine (Zinic et al., Positionally Isomeric Organic Gelators: Structure-Gelation Study, Racemic versus Enantiomeric Gelators, and Solvation Effects, Chem. Eur. J. 2010; 16:3066-82).

Sources & evidence

ORD record
ord-4e127cdbee584fd48a1f74d53939a02e
Source dataset
uspto-grants-2015_02
Patent number
US08945897B2

Reaction notes

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