Triethylamine → HCID 66784724, compound

Participants

Reaction Steps

To a solution of D2 (0.73 g, 2.709 mmol) in dry DCM (8 ml), cooled at 0° C., were added Et3N (0.562 ml, 4.064 mmol) and cyclopropyl-acetyl chloride (0.385 g, 3.251 mmol). The resulting reaction mixture was stirred at room temperature for 16 h. To this mixture was then added NaHCO3 (aqueous sat. solution). The resulting solution was then extracted with DCM. The organic layer was separated, dried (MgSO4) and concentrated in vacuo to yield intermediate compound D3 (0.94 g, 99%).

Provenance & Evidence