2-[(Piperidin-4-yl)oxy]acetamide → HCID 71735092, compound

HRID 1842013Notes

Reaction equation

HRID 1842013 reaction equation
C(OC(N1C[CH2:12][N:11]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([C@@H:21]3[O:30][C:25]4=[N:26][CH:27]=[CH:28][CH:29]=[C:24]4[O:23][CH2:22]3)=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.N1CC[CH:34]([O:37][CH2:38][C:39]([NH2:41])=[O:40])[CH2:33]C1>>[O:23]1[C:24]2[C:25](=[N:26][CH:27]=[CH:28][CH:29]=2)[O:30][C@@H:21]([C:18]2[CH:17]=[CH:16][C:15]([CH2:14][N:11]3[CH2:12][CH2:33][CH:34]([O:37][CH2:38][C:39]([NH2:41])=[O:40])[CH2:9][CH2:10]3)=[CH:20][CH:19]=2)[CH2:22]1

Participants

3

Reactant 2

HCID 425534032-[(Piperidin-4-yl)oxy]acetamideHCID 866953624-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 71735092HCID 71735092, compound

Procedure

Compound 274 is synthesized from Intermediate C and 2-(piperidin-4-yloxy)acetamide according to General Method K. (LC/MS method 16: ES+ m/z 384.3 [M+H]+, Rt=0.32 min)

Sources & evidence

ORD record
ord-9a3961794c414da99a4aac00e896fc96
Source dataset
uspto-grants-2015_02
Patent number
US08946203B2

Reaction notes

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