Hydrochloric Acid → HCID 66634452, compound

Participants

Reaction Steps

To a solution of methyl 5-(4-(2-fluorobenzyl)thiomorpholine-2-carboxamido)-1H-indazole-3-carboxylate (250 mg, 0.58 mmol) in THF (4 mL), was added LiOH (1.2 mL, 1M, 1.2 mmol). The resulted solution was stirred at RT for overnight. 1 N HCl was added to the reaction mixture until pH reached around 4. The solvent was removed and the residual was used directly for the next step. LC-MS: 415.1 [M+H]

Provenance & Evidence