Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopropylacetylene → HCID 57827602, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopropylacetylene | HCID 138823 | — |
| 반응물 | Ethyl 5-bromopicolinate | HCID 12686158 | — |
| 촉매 | Copper iodide | HCID 83717 | — |
| 촉매 | HCID 178418397 | HCID 178418397 | — |
| 용매 | Diisopropylamine | HCID 7912 | — |
| 생성물 | HCID 57827602 | HCID 57827602 | — |
반응 단계
Cyclopropylacetylene (73.7 μL), copper iodide (3.16 mg) and tetrakis(triphenylphosphine)palladium (9.59 mg) were added to a solution of ethyl 5-bromopyridine-2-carboxylate (95.5 mg) in diisopropylamine (2 mL) at room temperature, and the mixture was stirred at room temperature for 17 hours and five minutes. The reaction solution was concentrated under reduced pressure. The residue was purified by NH-silica gel column chromatography to obtain the title compound (19.4 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08946211B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-b985d8f4ca0c4a05a8142db7a31ef0a8 |
| 출처 메모 | uspto-grants-2015_02 |