1-(2-Pyrimidinyl)piperazine → HCID 11713254, compound

HRID 1842302Notes

Reaction equation

HRID 1842302 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:24]2[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)[C:5]2[S:10][C:9]([CH2:11][N:12]3[CH2:17][CH2:16][N:15]([C:18]4[N:23]=[CH:22][CH:21]=[CH:20][N:19]=4)[CH2:14][CH2:13]3)=[CH:8][C:6]=2[N:7]=1.[N:30]1[CH:35]=[CH:34][CH:33]=[N:32]C=1N1CCNCC1>>[NH:32]1[C:33]2[C:34](=[C:4]([C:2]3[N:3]=[C:4]([N:24]4[CH2:29][CH2:28][O:27][CH2:26][CH2:25]4)[C:5]4[S:10][C:9]([CH2:11][N:12]5[CH2:17][CH2:16][N:15]([C:18]6[N:23]=[CH:22][CH:21]=[CH:20][N:19]=6)[CH2:14][CH2:13]5)=[CH:8][C:6]=4[N:7]=3)[CH:5]=[CH:6][CH:8]=2)[CH:35]=[N:30]1

Participants

3

Reactant 2

HCID 887471-(2-Pyrimidinyl)piperazineHCID 57493978HCID 57493978, compound

Product 1

HCID 11713254HCID 11713254, compound

Procedure

Prepared via 2-Chloro-4-morpholin-4-yl-6-(4-pyrimidin-2-yl-piperazin-1-ylmethyl)-thieno[3,2-d]pyrimidine, prepared from 1-(2-pyrimidyl)piperazine.

Sources & evidence

ORD record
ord-d768fa3b3028439e9c9a1c74a117ea69
Source dataset
uspto-grants-2015_02
Patent number
US08946217B2

Reaction notes

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