Pentane, 1-bromo-4-methyl- → HCID 50915677, compound

HRID 1842370Notes

Reaction equation

HRID 1842370 reaction equation
[Cl:1][C:2]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11](=[O:21])[CH2:12][NH:13][C:14]2[C:15](=[O:20])[NH:16][N:17]=[CH:18][CH:19]=2)[CH2:7][CH2:6]1.Br[CH2:31][CH2:32][CH2:33][CH:34]([CH3:36])[CH3:35]>>[Cl:1][C:2]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:27])[F:28])=[CH:22][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11](=[O:21])[CH2:12][NH:13][C:14]2[C:15](=[O:20])[N:16]([CH2:31][CH2:32][CH2:33][CH:34]([CH3:36])[CH3:35])[N:17]=[CH:18][CH:19]=2)[CH2:7][CH2:6]1

Participants

3

Reactant 2

HCID 69385Pentane, 1-bromo-4-methyl-HCID 50915333HCID 50915333, compound

Product 1

HCID 50915677HCID 50915677, compoundYield 33%

Procedure

Compound 47 is prepared from intermediate 7b and from 1-bromo-4-methyl-pentane following synthesis method 6 (yield: 33%).

Sources & evidence

ORD record
ord-73f958d661a44476bed4f5abab4b9a1e
Source dataset
uspto-grants-2015_02
Patent number
US08946225B2

Reaction notes

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