1,3-Dibromopropane → HCID 57517457, compound

Participants

Reaction Steps

To a stirred solution of diethyl 1H-pyrrole-2,4-dicarboxylate (2 g, 9.47 mmol) and 1,3-dibromopropane (10 mL, 98 mmol) in acetonitrile was added potassium carbonate (1.7 g, 12.3 mmol). The mixture was refluxed overnight, then filtered and concentrated to give crude diethyl 1-(3-bromopropyl)-1H-pyrrole-2,4-dicarboxylate. 1H NMR (CDCl3, 300 MHz) δ7.47 (s, 1H), 7.36 (s, 1 H), 4.47 (t, J=6.6 Hz, 2 H), 4.27 (m, 4 H), 3.32 (t, J=6.2 Hz, 2 H), 2.32 (m, 2 H), 1.34 (m, 6 H).

Provenance & Evidence