HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1842487Generated: November 2, 2026
Tert-butyl 3-(2-amino-4-methylphenylcarbamoyl)azetidine-1-carboxylate → HCID 178423469, compound
https://huagongshe.com/reaction/1842487
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tert-butyl 3-(2-amino-4-methylphenylcarbamoyl)azetidine-1-carboxylate | HCID 58548457 | — |
| Reactant | Tert-butyl 3-(2-amino-5-methylphenylcarbamoyl)azetidine-1-carboxylate | HCID 58548488 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178423469 | HCID 178423469 | — |
Reaction Steps
A solution of tert-butyl 3-(2-amino-4-methylphenylcarbamoyl)azetidine-1-carboxylate and tert-butyl 3-(2-amino-5-methylphenylcarbamoyl)azetidine-1-carboxylate (prepared in the previous step) in AcOH (40 mL) was heated to 100° C. for 1.5 h and concentrated. The product tert-butyl 3-(5-methyl-1H-benzo[d]imidazol-2-yl)azetidine-1-carboxylate was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08946230B2 |
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| Source dataset | uspto-grants-2015_02 |
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| ORD ID | ord-642238df95114d4fa20e813eb6d9de42 |
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| Source note | uspto-grants-2015_02 |
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