1-(3-Bromophenyl)propan-2-one → N-{5-[3-(2-oxopropyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

HRID 18426Notes

Reaction equation

HRID 18426 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[CH2:14][CH:13]([NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])[CH2:12]3)O1.Br[C:27]1[CH:28]=[C:29]([CH2:33][C:34](=[O:36])[CH3:35])[CH:30]=[CH:31][CH:32]=1>>[O:36]=[C:34]([CH3:35])[CH2:33][C:29]1[CH:28]=[C:27]([C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[CH2:14][CH:13]([NH:18][S:19]([CH:22]([CH3:23])[CH3:24])(=[O:20])=[O:21])[CH2:12]3)[CH:32]=[CH:31][CH:30]=1

Participants

3

Reactant 2

HCID 27340931-(3-Bromophenyl)propan-2-oneHCID 46899971N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

Product 1

HCID 11552469N-{5-[3-(2-oxopropyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

Procedure

The title compound was prepared from N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide and 1-(3-bromophenyl)-2-propanone in a similar manner to Example 1.

Sources & evidence

ORD record
ord-ba8f21bce08e4b7abcf93116021a7f52
Source dataset
uspto-grants-2010_06
Patent number
US07741351B2

Reaction notes

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