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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 184292Generated: October 26, 2026

2-Amino-4-(4-hydroxyphenyl)thiophene-3-carbonitrile → methyl 5-(3-(4-(5-amino-4-cyanothiophen-3-yl)phenoxy)propyl)-2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylate

https://huagongshe.com/reaction/184292

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-(4-hydroxyphenyl)thiophene-3-carbonitrileHCID 15219960—
Reactantmethyl 2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-hydroxypropyl)thiazole-4-carboxylateHCID 59447477—
Reactantethyl 5-(4-((4-(5-amino-1-(tert-butoxycarbonyl)-4-cyano-1H-pyrazol-3-yl)phenoxy)methyl)phenyl)-2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylateHCID 59447596—
Reactanttert-butyl 5-amino-4-cyano-3-(4-hydroxyphenyl)-1H-pyrazole-1-carboxylateHCID 136027725—
Productmethyl 5-(3-(4-(5-amino-4-cyanothiophen-3-yl)phenoxy)propyl)-2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylateHCID 59447498—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-58eec88f8ad248b9a9d215caef4bb5d6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)