Ammonia → N-[2-benzyl-1-[2-(4-chlorophenyl)acetyl]piperidin-4-yl]-2,2,2-trifluoro-N-(quinolin-4-ylmethyl)acetamide
Reaction equation
[CH2:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH:23]1[NH:24][CH2:25][CH2:26][CH:27]([N:29]([C:30]([C:31]([F:32])([F:33])[F:34])=[O:35])[CH2:36][c:37]2[cH:38][cH:39][n:40][c:41]3[cH:42][cH:43][cH:44][cH:45][c:46]23)[CH2:28]1.[CH2:48]([Cl:49])[Cl:50].[NH3:47].[OH:1][C:2](=[O:3])[CH2:4][c:5]1[cH:6][cH:7][c:8]([Cl:9])[cH:10][cH:11]1.[S:12]([Cl:13])([Cl:14])=[O:15]>>[C:2](=[O:3])([CH2:4][c:5]1[cH:6][cH:7][c:8]([Cl:9])[cH:10][cH:11]1)[N:24]1[CH:23]([CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:28][CH:27]([N:29]([C:30]([C:31]([F:32])([F:33])[F:34])=[O:35])[CH2:36][c:37]2[cH:38][cH:39][n:40][c:41]3[cH:42][cH:43][cH:44][cH:45][c:46]23)[CH2:26][CH2:25]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7f4a60542dfa400897d7d3a7861ab5f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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