HCID 58542524, compound → HCID 58542578, compound
Reaction equation
FC(F)OC1C=C(C(O)=O)N(C)N=1.[CH:14]1([C:17]2[C:21]([C:22]([F:25])([F:24])[F:23])=[C:20]([C:26]([O:28]CC)=[O:27])[N:19]([CH3:31])[N:18]=2)[CH2:16][CH2:15]1>>[CH:14]1([C:17]2[C:21]([C:22]([F:23])([F:24])[F:25])=[C:20]([C:26]([OH:28])=[O:27])[N:19]([CH3:31])[N:18]=2)[CH2:15][CH2:16]1Participants
3
Procedure
This compound is prepared analogously to the preparation of 3-(difluoromethoxy)-1-methyl-1H-pyrazole-5-carboxylic acid from ethyl 3-cyclopropyl-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylate:
Sources & evidence
- ORD record
- ord-d35fd188f41d456e9548fdbf0ef213b5
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08946234B2
Reaction notes
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