Iodine → HCID 58542512, compound

HRID 1843093Notes

Reaction equation

HRID 1843093 reaction equation
[CH:1]1([C:4]2[C:8]([I:9])=[C:7]([C:10]([O:12][CH2:13]C)=[O:11])[N:6]([CH3:15])[N:5]=2)[CH2:3][CH2:2]1.CN1C(C(OC)=O)=CC(C2C=C[C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][CH:27]=2)=N1.II>>[I:9][C:8]1[C:4]([C:1]2[CH:3]=[CH:2][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][CH:27]=2)=[N:5][N:6]([CH3:15])[C:7]=1[C:10]([O:12][CH3:13])=[O:11]

Participants

4

Reactant 3

HCID 807IodineHCID 13370527HCID 13370527, compoundHCID 58542506HCID 58542506, compound

Product 1

HCID 58542512HCID 58542512, compound

Procedure

This compound is prepared analogously to the preparation of ethyl 3-cyclopropyl-4-iodo-1-methyl-1H-pyrazole-5-carboxylate from methyl 1-methyl-3-[4-(trifluoromethyl)phenyl]-1H-pyrazole-5-carboxylate and iodine.

Sources & evidence

ORD record
ord-58019fe3b9dd4d01916fe7e55fae6862
Source dataset
uspto-grants-2015_02
Patent number
US08946234B2

Reaction notes

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