HCID 58542512, compound → HCID 58542552, compound
Reaction equation
[CH:1]1([C:4]2[C:8]([C:9]([F:12])([F:11])[F:10])=[C:7]([C:13]([O:15][CH2:16]C)=[O:14])[N:6]([CH3:18])[N:5]=2)[CH2:3][CH2:2]1.IC1C(C2C=C[C:33]([C:36]([F:39])([F:38])[F:37])=[CH:32][CH:31]=2)=NN(C)C=1C(OC)=O>>[CH3:18][N:6]1[C:7]([C:13]([O:15][CH3:16])=[O:14])=[C:8]([C:9]([F:10])([F:11])[F:12])[C:4]([C:1]2[CH:3]=[CH:2][C:33]([C:36]([F:39])([F:38])[F:37])=[CH:32][CH:31]=2)=[N:5]1Participants
3
Procedure
This compound is prepared analogously to the preparation of ethyl 3-cyclopropyl-1-methyl-4-(trifluoromethyl)-1H-pyrazole-5-carboxylate from methyl 4-iodo-1-methyl-3-[4-(trifluoromethyl)phenyl]-1H-pyrazole-5-carboxylate.
Sources & evidence
- ORD record
- ord-ac4f5f438a4d45ca96764b5782082531
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08946234B2
Reaction notes
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