HCID 58542552, compound → HCID 58542587, compound
Reaction equation
FC(F)OC1C=C(C(O)=O)N(C)N=1.[CH3:14][N:15]1[C:19]([C:20]([O:22]C)=[O:21])=[C:18]([C:24]([F:27])([F:26])[F:25])[C:17]([C:28]2[CH:33]=[CH:32][C:31]([C:34]([F:37])([F:36])[F:35])=[CH:30][CH:29]=2)=[N:16]1>>[CH3:14][N:15]1[C:19]([C:20]([OH:22])=[O:21])=[C:18]([C:24]([F:25])([F:26])[F:27])[C:17]([C:28]2[CH:33]=[CH:32][C:31]([C:34]([F:35])([F:36])[F:37])=[CH:30][CH:29]=2)=[N:16]1Participants
3
Procedure
This compound is prepared analogously to the preparation of 3-(difluoromethoxy)-1-methyl-1H-pyrazole-5-carboxylic acid from methyl 1-methyl-4-(trifluoromethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazole-5-carboxylate.
Sources & evidence
- ORD record
- ord-746aa539dbc34364ad6307883fe21cba
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08946234B2
Reaction notes
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