Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | CC 5013 hydrochloride | HCID 44234581 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Lenalidomide | HCID 216326 | — |
Reaction Steps
The filtered lenalidomide hydrochloride was resuspended in methanol (500 ml) and triethylamine (1.1 mole equivalent) was slowly added to the reaction mixture. The reaction mixture was cooled to 5-10° C. and the liberated lenalidomide was filtered, washed with methanol and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08946265B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-8f89a87239754c5281a06b3274869598 |
|---|
| Source note | uspto-grants-2015_02 |
|---|
