m-Trifluoromethylphenylacetonitrile → Phenethylamine, m-trifluoromethyl-

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Reaction Steps

Using analogous reaction conditions as described in Example 16, step 1, (3-trifluoromethyl-phenyl)-acetonitrile (2 g, 10.81 mmol) in methanolic ammonia (50 mL) was reacted with to Raney nickel (400 mg) to afford 2 g of the product (97.89% yield).

Provenance & Evidence