HCID 1080325, compound → HCID 18997341, compound

Participants

Reaction Steps

Using analogous reaction conditions and workup as described in Example 1, 1-ethyl-3-(2-nitro-vinyl)-1H-indole (4.8 g, 22.018 mmol) in dry THF (25 mL) was reacted with LAH (4.17 g, 110.091 mmol) in dry THF (25 mL). The resulting mixture was refluxed for 16 hours under nitrogen atmosphere to afford 4.1 g of the product (98% yield).

Provenance & Evidence