HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitromethane → 2-Fluoro-4-(2-nitro-vinyl)-1-trifluoromethyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Fluoro-4-(trifluoromethyl)benzaldehyde | HCID 2737537 | — |
| Product | 2-Fluoro-4-(2-nitro-vinyl)-1-trifluoromethyl-benzene | HCID 123914147 | 46.6% |
Reaction Steps
3-Fluoro-4-trifluoromethyl-benzaldehyde (5 g, 25.9 mmol) was reacted with nitro methane (1.58 g, 25.9 mmol), 10N NaOH (1.08 g, 27.20 mmol) to afford 2.8 g of the product (46.6% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946260B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-f53a088457954a72bc17894eea196c25 |
| Source note | uspto-grants-2015_02 |