HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluorophenyl)hydrazine → HCID 59198430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluorophenyl)hydrazine | HCID 69982 | — |
| Reactant | 4-Hydroxy-2(1H)-pyridinone | HCID 54696004 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 59198430 | HCID 59198430 | 18.1% |
Reaction Steps
4-Hydroxypyridin-2(1H)-one (1 g, 0.009 mol) and (4-fluorophenyl)hydrazine (3.6 g, 0.027 mol) in diphenyl ether (20 mL) were heated at 250° C. for 5 hours to afford the crude product. Purification by washing with hexane, followed by column chromatography on silica gel (1.5% methanol in DCM) afforded 330 mg of the product (17.36% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946260B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-37f215ea493b49a39239628c58830740 |
| Source note | uspto-grants-2015_02 |