HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Fluorophenyl)-2-propenoic acid → 3-(3-Fluorophenyl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Fluorophenyl)-2-propenoic acid | HCID 88606 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(3-Fluorophenyl)propionic acid | HCID 2737489 | 80.69% |
Reaction Steps
3-(3-Fluorophenyl)acrylic acid (I-78a: 6.4 gm, 38.5 mmol) in methanol (100 mL) was reduced with 10% Pd/C (640 mg) to afford the crude product, 5 g (80.69% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946260B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-7a510fce0be64052bf67aa17848ce7a5 |
| Source note | uspto-grants-2015_02 |