2-(Trifluoromethyl)benzenepropanoic acid → HCID 86731076, compound

HRID 1844398Notes

Reaction equation

HRID 1844398 reaction equation
Cl.[Cl:2][C:3]1[CH:4]=[C:5]([CH2:10][CH2:11][CH2:12][NH2:13])[CH:6]=[CH:7][C:8]=1Cl.[F:14][C:15]([F:28])([F:27])C1C=CC=CC=1CCC(O)=O>>[ClH:2].[F:14][C:15]([F:28])([F:27])[C:6]1[CH:7]=[CH:8][CH:3]=[CH:4][C:5]=1[CH2:10][CH2:11][CH2:12][NH2:13]

Participants

3

Reactant 2

HCID 152848092-(Trifluoromethyl)benzenepropanoic acidHCID 717443353-(3,4-Dichlorophenyl)propan-1-amine--hydrogen chloride (1/1)

Product 1

HCID 86731076HCID 86731076, compound

Procedure

Intermediate 4 was prepared according to the procedures described in Intermediate 1 using 3-(2-(trifluoromethyl)phenyl)propanoic acid as the starting material. LC-MS (ESI) m/z 204.0 (M+H)+, RT=1.40 min (Method B).

Sources & evidence

ORD record
ord-7cf019c27fad45a8ac333b6dedcd42ee
Source dataset
uspto-grants-2015_02
Patent number
US08946430B2

Reaction notes

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