5-Methoxyisatin → HCID 86731086, compound

Participants

Reaction Steps

Intermediate 27 was prepared as a white powder following the procedure described for Intermediate 16 by replacing indoline-2,3-dione with 5-methoxyindoline-2,3-dione. 1H NMR (400 MHz, DMSO-d6) δ ppm 12.20 (1 H, s), 10.22 (1 H, br. s.), 7.27 (1H, d, J=8.8 Hz), 7.04 (1H, dd, J=9.1, 2.5 Hz), 6.82 (1 H, d, J=2.5 Hz), 4.41 (2 H, q, J=7.1 Hz), 3.32 (3 H, s), 1.35 (3 H, t, J=7.1 Hz). LC-MS (ESI) m/z 264.0 (M+H), RT=1.64 min (Method B).

Provenance & Evidence