Dimethylamine → (6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-dimethyl-amine
Reaction equation
CNC.[Br:4][C:5]1[CH:6]=[CH:7][C:8]2[N:9]([N:11]=[C:12]([N:14]3[CH2:19]COC[CH2:15]3)[N:13]=2)[CH:10]=1>>[Br:4][C:5]1[CH:6]=[CH:7][C:8]2[N:9]([N:11]=[C:12]([N:14]([CH3:19])[CH3:15])[N:13]=2)[CH:10]=1Participants
3
Procedure
Using dimethylamine, this compound was prepared following the same method as for the synthesis of 6-bromo-2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridine White solid (0.65 g, 75%). MS: m/z=242 (M+H+).
Workup
- customthis compound was prepared
Sources & evidence
- ORD record
- ord-d66b6dec90f34bb69412ab1fbed66912
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08946427B2
Reaction notes
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