反应详情

The above-described product 18a (7.87 g, 27.7 mmol) was dissolved in ethanol (50 mL), together with Pd/C (0.787 g). The mixture was reacted overnight at room temperature with a flow of hydrogen. After completion of the reaction, the solvent was evaporated. After recrystallization with ethyl acetate/petroleum ether, the product 19a (5.9 g) was obtained as a yellow solid, with a yield of 83.4%.

1. customAfter completion of the reaction
2. customthe solvent was evaporated
3. customAfter recrystallization with ethyl acetate/petroleum ether