HCID 86675623, compound → HCID 53390690, compound

Participants

Reaction Steps

The compound (271 mg) obtained in Step 1 of this Example was heated to reflux for 2 hours in 5 N hydrochloric acid (10 mL). The reaction solution was concentrated, and the residue was then charged to Dowex 50WX8 (1.5 g) adjusted in advance with dilute hydrochloric acid and deionized water. The resin was washed with deionized water, followed by elution with 5% ammonia water. The eluate was concentrated to obtain the title compound (134 mg).

Provenance & Evidence