HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanemethylamine → HCID 86719133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanemethylamine | HCID 76688 | — |
| Reactant | HCID 70873097 | HCID 70873097 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 86719133 | HCID 86719133 | 93% |
Reaction Steps
To a solution of 5a (6.4 g, 22.2 mmol) in toluene (100 mL) was added cyclohexylmethanamine (2.8 g, 24.4 mmol) and TsOH (0.3 g). This mixture was refluxed for 20 h, cooled, concentrated and purified by CC to afford compound 5b (7.5 g, 93%) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946446B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-38c7a577a746408fb27b86cd800064c1 |
| Source note | uspto-grants-2015_02 |