Ammonia → (2-Amino-quinazolin-4-yl)-(4-methoxy-phenyl)-methylamine

HRID 184489Notes

Reaction equation

HRID 184489 reaction equation
[CH3:23][OH:24].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11]1.[NH3:22]>>[c:2]1([NH2:22])[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([N:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[n:11]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 887MethanolHCID 117381122-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine

Product 1

HCID 11323466(2-Amino-quinazolin-4-yl)-(4-methoxy-phenyl)-methylamine

Sources & evidence

ORD record
ord-872b49766ffc42eda9738dff638b39ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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