Benzene, 1-(bromomethyl)-3-nitro- → 6-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl]-2-(3-nitrobenzyl)-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[N+:32](=[O:33])([O-:34])[c:35]1[cH:36][c:37]([CH2:38][Br:39])[cH:40][cH:41][cH:42]1.[c:1]1([CH:7]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]4[c:23]([cH:24]3)[C:22](=[O:25])[NH:21][CH2:20]4)[CH2:14][CH2:15]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]4[c:23]([cH:24]3)[C:22](=[O:25])[N:21]([CH2:38][c:37]3[cH:36][c:35]([N+:32](=[O:33])[O-:34])[cH:42][cH:41][cH:40]3)[CH2:20]4)[CH2:14][CH2:15]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-4a9b7b1b0d75457fa7d3f3da8ad491e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…